Date: March 7th, 2016
Time: 1:00 pm to 5:30 pm
Venue: FAPESP – Rua Pio XI, 1500 - São Paulo/ SP - Brazil
The Workshop will bring together world experts from academy and pharmaceutical industry to discuss the state-of-the-art of targeting kinase in human diseases, which has experienced a resurgent interest in the recent years. Speakers will present their most current findings in the kinase field and will discuss strategies for efficient targeting of kinases using small molecules. They will also highlight the impact of using an open access model to accelerate discoveries for new drugs and to facilitate the establishment of collaborative programs between public and private sectors.
About the SGC and SGC-UNICAMP:
The SGC is a public-private partnership that supports the discovery of new medicines through open source research that conduct pre-competitive research to facilitate the discovery of new medicines and has research sites at the University of Oxford, University of Toronto (Canada), University of Campinas (Brazil), and University of North Carolina (USA).
The SGC-UNICAMP Center funded by FAPESP, UNICAMP and SGC, is focused on developing molecular probes for protein kinases regulating RNA splicing and chromatin, with strong links to the other SGC laboratories and our network of industrial funders and academic collaborators. In addition to targeting human physiology, we will also utilize the chemical probes to investigate the roles of protein kinases in plants, with an emphasis on promoting resistance to adverse conditions and improving yields of agriculturally-significant crops.
Preclinical target validation using patient-derived cells
Edwards AM, Arrowsmith CH, Bountra C, Bunnage ME, Feldmann M, Knight JC, Patel DD, Prinos P, Taylor MD, Sundström M; SGC Open Source Target-Discovery Partnership.
Nat Rev Drug Discov. 2015 Mar;14(3):149-50. doi: 10.1038/nrd4565. Epub 2015 Feb 20.
The promise and peril of chemical probes
Nat Chem Biol. 2015 Aug;11(8):536-41. doi: 10.1038/nchembio.1867.
Prof Dr Paulo Arruda: Centro de Biologia Molecular e Engenharia Genética (CBMEG-UNICAMP)
MSc Nathalia Zocal: Structural Genomics Consortium, UNICAMP, BR
Prof Dr Aled Edwards: Structural Genomics Consortium, University of Toronto, CA
Dr Katlin B Massirer: Centro de Biologia Molecular e Engenharia Genética (CBMEG-UNICAMP) and Structural Genomics Consortium, UNICAMP, BR
Dr Opher Gileadi: Structural Genomics Consortium, UNICAMP, BR
Dr Rafael Counago: Structural Genomics Consortium, UNICAMP, BR
Dr William Zuercher: 4Structural Genomics Consortium, University of North Carolina, USA
Event free of charge / Limited registration
Official language: English
(Simultaneous translation will not be provided)
Information: FAPESP / Tel.: (11) 3838.4216 / firstname.lastname@example.org
Pio Park - Rua Pio XI, 1320 | Tonimar – Rua Jorge Americano 89